MZresearch notebook · v2.0

FIELD NOTES / Scientific AI Systems

Research OS

Validated PrototypeEvidence B

How can a computational result be traced to its inputs, validation checks and permitted scientific claims?

Last reviewed 2026-10-19 · Non-sensitive overview of private work

Overview

Biomedical research reliability · Research OS

记录分析输入、验证过程,以及结果能够支持哪些科学结论。

Research Question

How can a computational result be traced to its inputs, validation checks and permitted scientific claims?

Technical Approach

Versioned evidence contracts, a local tabular runtime, analysis and prediction adapters, leakage/calibration checks, claim gates and read-only interface projections. The inspected v0.4 runtime is deterministic and does not use an LLM; separate research modules explore scientific evidence governance.

PythonpandasSciPystatsmodelsscikit-learnSQLiteReactTypeScript
  1. Local tabular input
  2. Versioned plan
  3. Analysis / prediction
  4. Scientific validation
  5. Permitted claims + human review
Architecture diagram based on the v0.4 source code. The local runtime uses deterministic analysis and validation; LLM calls and manuscript generation are outside its scope.

My Contribution

Developed local research workflow prototypes, evidence contracts, validation gates and scientific audit packages. Each prototype addresses a defined stage of the research process.

Evidence

  • Source-inspected runtime: intake → analysis/prediction → validation → claim permissions.
  • Scientific invariant tests cover causality boundaries, leakage, calibration and reproducibility.
  • Read-only SHA256 verification confirmed the integrity of the frozen writing package. Scientific validity requires separate evaluation.

Outputs

  • Local tabular analysis/prediction runtime
  • Versioned claim and validation contracts
  • Read-only research interface prototype
  • Frozen evidence and writing preparation package

Current Status

Validated PrototypeEvidence B

Prototype scope. No claim of production readiness, autonomous discovery, clinical utility or a published Research OS paper.

Related Publications

No project-specific peer-reviewed publication is listed. Ongoing work is kept separate from the published bibliography.